What is zonisamide prescribed for?
Descriptions. Zonisamide is used together with other medicines to control partial seizures (convulsions) in the treatment of epilepsy. This medicine is an anticonvulsant that works in the brain to stop seizures. This medicine is available only with your doctor’s prescription.
What is the side effect of zonisamide?
Dizziness, drowsiness, trouble sleeping, lack of coordination, lightheadedness, loss of appetite, diarrhea, or double vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What are the long term side effects of zonisamide?
Table 2
| Adverse effect | Leppik20* | Leppik et al19*,& |
|---|---|---|
| Anorexia or decreased appetite | 201 (16.7%) | 17 (15%) |
| Fatigue or tiredness or asthenia | 182 (15.1%) | 10 (8.8%) |
| Nausea | 159 (13.2%) | 17 (15%) |
| Headache | 145 (12%) | 18 (15.9%) |
Is zonisamide the same as gabapentin?
Are Gabapentin and Zonegran the Same Thing? Zonegran (zonisamide) and gabapentin are anticonvulsants used to treat seizures in patients with epilepsy. Gabapentin is also used to treat nerve pain caused by shingles (herpes zoster). Brand names for gabapentin include Nurontin, Gralise, Neuraptine, and SmartRx Gaba-V Kit.
Can zonisamide cause kidney problems?
Zonisamide may cause serious allergic reactions called drug reaction with eosinophilia and systemic symptoms (DRESS) or multiorgan hypersensitivity, which may damage the liver, kidney, blood, heart, or muscles.
Does zonisamide affect memory?
Zonisamide administered in a high, acute dose impairs the spatial memory. The drug given repeatedly disturbs spatial memory in the initial phase of the study. Zonisamide administered repeatedly impairs emotional memory.
Does zonisamide affect the kidneys?
Can zonisamide be used for nerve pain?
Zonisamide is one of a type of medicine normally used to treat epilepsy. Some of these medicines are also useful for treating neuropathic pain. We looked for clinical trials that used zonisamide to treat neuropathic pain. We found a single study with 25 participants treated either with zonisamide or placebo.
Does zonisamide cause bone loss?
These results suggest that zonisamide may cause bone loss by accelerating bone resorption rather than inhibiting bone formation. Moreover, the bone loss induced by zonisamide could be prevented by combining zonisamide with alfacalcidol.
What are the uses of zonisamide?
Zonisamide is used together with other medicines to treat partial seizures in adults and teenagers at least 16 years old. Zonisamide may also be used for purposes not listed in this medication guide. Taking zonisamide can cause permanent vision loss. Tell your doctor right away if you have any eye pain or redness or any changes in your vision.
What is the pKa of zonisamide?
Zonisamide is a white powder, pKa = 10.2, and is moderately soluble in water (0.80 mg/mL) and 0.1 N HCl (0.50 mg/mL). The chemical structure is: ZONEGRAN is supplied for oral administration as capsules containing 25 mg or 100 mg zonisamide.
What is the empirical formula for zonisamide?
The empirical formula is C 8 H 8 N 2 O 3 S with a molecular weight of 212.23. Zonisamide is a white powder, pKa = 10.2, and is moderately soluble in water (0.80 mg/mL) and 0.1 N HCl (0.50 mg/mL). The chemical structure is: ZONEGRAN is supplied for oral administration as capsules containing 25 mg or 100 mg zonisamide.
What are the ingredients in zonisamide?
ZONEGRAN is supplied for oral administration as capsules containing 25 mg or 100 mg zonisamide. Each 25 mg capsule contains the labeled amount of zonisamide plus the following inactive ingredients: microcrystalline cellulose, hydrogenated vegetable oil, sodium lauryl sulfate, gelatin, and titanium dioxide.