What is the role of DNA glycosylases in base excision repair?
What is the role of DNA glycosylases in base excision repair? DNA glycosylases recognize and remove damaged bases from DNA by cleaving the base–sugar (N-glycosylic) bond, and downstream base excision repair enzymes restore the correct nucleotide. Does base excision repair require DNA polymerase? BER requires only four or five enzymes in the basic reaction steps