What is ICAM in immunology?
The intercellular adhesion molecule (ICAM) 1 is an Ig-like cell adhesion molecule expressed by several cell types, including leukocytes and endothelial cells.
Is ICAM an immunoglobulin?
Structure. ICAM-1 is a member of the immunoglobulin superfamily, the superfamily of proteins including antibodies and T-cell receptors.
Is ICAM a receptor?
The membrane-bound form of ICAM-1 serves as a counter receptor for the β2-integrins, CD11a/CD18 (LFA-1) and CD11b/CD18 (Mac-1), found on leukocytes.
What is ICAM biology?
In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily. They are important in inflammation, immune responses and in intracellular signalling events.
Where is ICAM expressed?
Although ICAM-1 is expressed constitutively at low levels on endothelial cells and on some lymphocytes and monocytes, its expression can be significantly increased in the presence of cytokines (TNFalpha, IL-1, IFNgamma) and reactive oxygen species.
How do you use ICAM?
Video: Simple remote video surveillance
- Step 1: Set up iCam on your computer(s) Head to http://skjm.com/icam/support.php and download iCamSource for Mac or PC.
- Step 2: Install iCam on your Android or iOS device. With your cameras set up, you’re ready to start remotely viewing the surveillance with your mobile device.
Where are ICAMs found?
leukocytes
The membrane-bound form of ICAM-1 serves as a counter receptor for the β2-integrins, CD11a/CD18 (LFA-1) and CD11b/CD18 (Mac-1), found on leukocytes. Interactions with membrane-bound ICAM-1 facilitate leukocyte transmigration across the endothelium of many cell types.
What is the difference between ICAM and VCAM?
ICAM (CD-54) is a ligand for the cell adhesion receptor LFA-1, shown to be important in immune stimulation that is upgraded in inflammatory cutaneous disorders. VCAM (CD-106) is an adhesion molecule normally found in stimulated endothelium, that plays a critical role in the migration of leukocytes.
What does ICAM 2 do?
ICAM-2 molecules regulate spermatid adhesion on Sertoli cell on the apical side of the blood-testis barrier (towards the lumen), thus playing a major role in spermatogenesis. This protein may also play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion.
What is iCam camera?
iCam is the mobile application for iOS (iPhone, iPod touch, and iPad) and Android devices that allows you to remotely monitor live video and audio feeds from up to 12 (iPhone / iPod touch / Android) or 16 (iPad) computer webcams at the same time.
How much is an iCam?
iCam Intraoral Camera
| Product Description | Price |
|---|---|
| iCAM INTRAORAL CAMERA 274-1100 Denterprise 01MAG10000 | $199.95 |