What does follicular fluid consist of?

What does follicular fluid consist of?

Follicular fluid (FF) is a liquid composed primarily of hormones, enzymes, anticoagulants, electrolytes, reactive oxygen species and antioxidants, which fills the follicular antrum and acts as an important mediator in the communication between cells in the antral follicle while bathing and carrying nutrients to the …

What is the colour of follicular fluid?

Follicular fluid is a complex extracellular fluid, semi-viscous and yellow in colour, which accumulates in the antrum of ovarian follicles during their growing phase. Follicular fluid provides the microenvironment within which the cumulus-oocyte complex matures and granulosa cells differentiate.

What is FF in follicular study?

Follicular fluid (FF) is a complex dynamic biological fluid that surrounds the developing oocyte. It is produced in growing antral follicles and contains a variety of molecules, such as proteins, steroid hormones, polysaccharides, metabolites, reactive oxygen species, and antioxidants.

What is the purpose of the follicular liquid of the vesicular follicle?

Follicular fluid (FF) provides nourishment for oocyte development. Proteins in FF regulate the external as well as internal environment of oocytes. As such, these proteins serve a critical role in fertilization as well as embryo development [64].

What is the role of progesterone in the follicular fluid?

P4 is an intra-follicular steroid that plays critical roles in resumption of oocyte meiosis, fertilization, embryonic development, implantation and maintenance of pregnancy [5–7]. Several studies determined high FF P4 concentrations to be predictive of subsequent implantation [8–11].

What is mature follicle?

Mature follicles were defined as 14 mm or more as measured on the day of ovulation trigger. Main outcomes and measures were rates of clinical pregnancy and multiple gestation. Results: We identified 24,649 women who underwent a total of 50,473 IUI cycles.

What happens corpus albicans?

As the corpus luteum is being broken down by macrophages, fibroblasts lay down type I collagen, forming the corpus albicans. This process is called “luteolysis”. The remains of the corpus albicans may persist as a scar on the surface of the ovary….

Corpus albicans
FMA 18620
Anatomical terminology

Does egg rupture mean ovulation?

This egg reaches maturity at about 18-22 mm size (about day 14) and then the follicle ruptures to release the egg which may now be fertilised by sperm. This process of egg rupture is known as ovulation.

Does egg rupture mean pregnancy?

After the egg release, if the sperm is already there, egg rupture pregnancy chances become higher, and a woman is most likely to get pregnant in the day after ovulation.

What is the role of antrum?

The antrum is the cavity around the ova which develops later in the development of the graafian follicle. It is the combination of blood plasma and secretory product of granulosa and theca cell. Following are its functions: (1) It provides microenvironment specific for the the development of the oocyte.

What do we know about proteins in human follicular fluid?

PANTHER showed HFF proteins were involved in complement and coagulation cascade, growth factor and hormone, immunity, and transportation, KEGG indicated their pathway, and STRING demonstrated their interaction networks. In comparison, 32% and 50% of proteins have not been reported in previous human follicular fluid and plasma.

Are proteins of human follicular fluid differentially regulated during ovulation?

The aim of the study was to identify, by use of a modern proteomic technique, proteins of human follicular fluid which are differentially regulated during ovulation of the natural menstrual cycle. Material and methods: This prospective experimental study over 3 years included women planned for laparoscopic sterilization.

Does human follicular fluid contribute to in vitro fertilization?

Background: Human follicular fluid (HFF) provides a key environment for follicle development and oocyte maturation, and contributes to oocyte quality and in vitro fertilization (IVF) outcome.

What are the biomarkers of infertility and IVF outcome?

Those proteins associated with innate immunity, complement cascade, blood coagulation, and angiogenesis might serve as the biomarkers of female infertility and IVF outcome, and their pathways facilitated a complete exhibition of reproductive process.