What are the hazards associated with isocyanates?
Isocyanates include compounds classified as potential human carcinogens and known to cause cancer in animals. The main effects of hazardous exposures are occupational asthma and other lung problems, as well as irritation of the eyes, nose, throat, and skin.
How do you protect from isocyanates?
Preventing exposure to isocyanates is a critical step in eliminating the health hazard. Engineering controls such as closed systems and ventilation should be the principal method for minimizing isocyanate exposure in the workplace.
Is isocyanates a hazardous material?
Isocyanates are hazardous chemicals. Isocyanates are widely used in manufacturing materials like polyurethane foams, rubbers, plastics, varnishes, adhesives and paints.
What is the most serious isocyanate health hazard?
Isocyanates can cause serious respiratory issues, including asthma. Isocyanates result from chemical reactions in plastics and polyurethanes. Workers who manufacture plastics or apply polyurethane coatings may be at risk of exposure.
What are the symptoms of isocyanate?
Exposure to isocyanates can lead to chemical bronchitis and pneumonitis. An isocyanate reaction often includes coughing, tightness of the chest, shortness of breath, nausea, vomiting, eye and skin irritations, gastric pain and loss of consciousness.
What is isocyanate poisoning?
Exposure to methyl isocyanate typically occurs through inhalation or dermal absorption. Toxicity might develop over 1 to 4 hours after exposure. Signs and symptoms of methyl isocyanate typically include cough, dyspnea, chest pain, lacrimation, eyelid edema, and unconsciousness.
How do you test for isocyanate exposure?
A urine sample is required and should be taken at the end (within an hour) of a period of potential exposure. Sampling should reflect normal working practice. Urine samples should be collected in bottles containing a citric acid preservative.
What are the treatment options for Isophorone diisocyanate toxicity?
Direct oral contact with isophorone diisocyanate contaminated persons or their gastric contents may result in self poisoning. 3. Remove and isolate contaminated clothing as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. 5. Wash exposed skin areas thoroughly with water. 6.
What are the hazards of isophorone diisocyanate exposure?
Exposure to high doses of isocyanates may produce fatal pulmonary edema or catarrh. Occupational asthma has been associated with isophorone diisocyanate exposure in the workplace and may occur through inhalation and dermal contact with this compound at workplaces where isophorone diisocyanate is produced or used.
What is the molecular formula of isophorone diisocyanate?
Isophorone diisocyanate PubChem CID 169132 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C12H18N2O2 or (CH3)2C6H7(CH3)(N=C=O)CH2N Synonyms ISOPHORONE DIISOCYANATE 4098-71-9 IPDI .
Isophorone diisocyanate adsorption is an important environmental fate process?
Isocyanates, such as isophorone diisocyanate, are hydrolyzed rapidly by water (1), indicating that adsorption is not an important environmental fate process (SRC). (1) Six C, Richter F; Ullmann’s Encyclopedia of Industrial Chemistry. 7th ed. (1999-2012).