How will you perform the assay of ephedrine HCL?

How will you perform the assay of ephedrine HCL?

ESTIMATION OF EPHEDRINE HCL. stirring, add about 30 ml acetic anhydride and make up the volume (1000 ml) with glacial acetic acid and keep the mixture for 24 hour. and renders the solution virtually anhydrous. anhydride because reaction between HClO4 and acetic anhydride is explosive.

How do official estimation of ephedrine hydrochloride is carried out?

Ephedrine Hydrochloride can be estimated as follows: Add about 30 ml of acetic anhydride to 900 ml glacial acetic acid and stir well after adding 8.5 ml of 72% HClO4 while stirring and keep the mixture for 24 hours.

What is the chemical formula of ephedrine?

C10H15NOEphedrine / Formula

What is non aqueous titration?

Non aqueous titration refers to a type of titration in which the analyte substance is dissolved in a solvent which does not contain water. Non Aqueous Titration Theory. The need for non aqueous titration arises because water can behave as a weak. base and a weak acid as well, and can hence compete in proton acceptance …

What is ephedrine sulfate used for?

Ephedrine Sulfate Injection, USP is indicated in the treatment of allergic disorders, such as bronchial asthma. The drug has long been used as a pressor agent, particularly during spinal anesthesia when hypotension frequently occurs.

What schedule is ephedrine?

Ephedrine and all Ephedra species which contain it are considered Schedule 4 substances under the Poisons Standard (October 2015).

What is the molecular formula for ephedrine?

Ephedrine PubChem CID 9294 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C10H15NO Synonyms Ephedrine l-Ephedrine (-)-Ephedrine 299-

What is ephedrine hydrochloride injection?

Ephedrine hydrochloride injection is on the WHO Model list of essentials for use in spinal anesthesia during delivery, to prevent hypotension. Its use requires specialized diagnostic or monitoring facilities, and/or specialist medical care, and/or specialist training.

How is ephedrine metabolized in humans?

Ephedrine, 8-20%, is metabolized in humans by N-demethylation to / phenylpropanolamin / PPA. A total of 4-13% of an oral dose of ephedrine undergoes oxidative deamination yielding 1-phenylpropan-1,2-diol and further side-chain oxidation to benzoic acid and hippuric acid.

What is the level of ephedrine in the Ebro River?

SURFACE WATER: (L)-Ephedrine was detected at levels generally ranging from about 0.7-100 ng/L in surface water and basin water samples collected from the Ebro River basin (Spain) during 2007 and 2008 sampling (1).