How is endometrial cancer graded and staged?
Endometrial cancer stages range from stage I (1) through IV (4). As a rule, the lower the number, the less the cancer has spread. A higher number, such as stage IV, means cancer has spread to other parts of the body. And within a stage, an earlier letter means a lower stage.
How is endometrial cancer classified?
Endometrial carcinoma has been traditionally divided into type 1 or endometrioid type that is usually moderate to well differentiated and type 2 that is usually poorly differentiated with high histologic grade and aggressive clinical behavior.
How many grades are there in endometrial cancer?
Grading endometrial cancer Grade 1 tumors have 95% or more of the cancer tissue forming glands. Grade 2 tumors have between 50% and 94% of the cancer tissue forming glands. Grade 3 tumors have less than half of the cancer tissue forming glands.
What is FIGO staging used for?
The FIGO (International Federation of Gynecology and Obstetrics) staging system is used most often for cancers of the female reproductive organs, including cervical cancer.
Can grade 1 endometrial cancer spread?
Grades 1 and 2 tumors are usually considered low-risk. They usually do not spread to other parts of the body.
Is grade 1 endometrial cancer curable?
Stage I uterine cancer is curable with surgery alone for the majority of patients.
What is serous endometrial cancer?
Uterine serous carcinoma (USC) is an aggressive variant of endometrial cancer that has not been well characterized. It accounts for less than 10% of all endometrial cancers and 80% of endometrial cancer–related deaths.
What types of uterine cancer are there?
There are two primary types of uterine cancer: endometrial cancer, which is more common, and uterine sarcoma, which is rare. In endometrial cancer, cancer cells form in the endometrium, which is the lining of the uterus.
What does FIGO Grade 3 mean?
We designate a tumor as FIGO grade 3 if the solid areas resemble poorly differentiated nonkeratinizing squamous cell carcinoma.
What does stage IB1 mean?
In stage IB1, the tumor is 2 centimeters or smaller and the deepest point of tumor invasion is more than 5 millimeters. In stage IB2, the tumor is larger than 2 centimeters but not larger than 4 centimeters. In stage IB3, the tumor is larger than 4 centimeters.
What are the stages of endometrial cancer?
Endometrial cancer stages range from stage I (1) through IV (4). As a rule, the lower the number, the less the cancer has spread. A higher number, such as stage IV, means cancer has spread to other parts of the body.
What is staging of endometrial cancer?
After a woman is diagnosed with endometrial cancer, doctors will try to figure out if it has spread and, if so, how far. This process is called staging. The stage of a cancer describes the amount of cancer in the body.
What is the FIGO staging system for endometrial cancer?
FIGO Staging System Surgical staging of endometrial cancer was first proposed in 1988, and the staging system was updated in 2009 (Table 2) (6). The previous iteration of the FIGO system subdivided stage I tumors into IA, IB, and IC tumors. Stage IA tumors were confined to the endometrial com- plex, stage IB tumors invaded only the inner
What happens after endometrial cancer is diagnosed?
After a woman is diagnosed with endometrial cancer, doctors will try to figure out if it has spread and, if so, how far. This process is called staging. The stage of a cancer describes the amount of cancer in the body. It helps determine how serious the cancer is and how best to treat it.