What is Valsartan and Hydrochlorothiazide used for?

What is Valsartan and Hydrochlorothiazide used for?

Description and Brand Names Valsartan and hydrochlorothiazide combination is used alone or with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries.

What is a USP drug monograph?

USP is an official quality standard for medicines marketed in the US. Monographs articulate the quality expectations for a medicine including for its identity, strength, purity, and performance. They also describe the tests to validate that a medicine and its ingredients meet these criteria.

What is the brand name for valsartan hydrochlorothiazide?

Valsartan/hydrochlorothiazide oral tablet is available as a brand-name drug and a generic drug. Brand name: Diovan HCT. Valsartan/hydrochlorothiazide comes as a tablet you take by mouth. Valsartan/hydrochlorothiazide is a combination of two drugs that work in different ways to treat high blood pressure.

Is valsartan a good blood pressure medicine?

Diovan (valsartan) is a medication used to lower blood pressure. It can also help protect the kidneys, so it is a good first-line option for people with both hypertension and diabetes.

What does USP mean on medication?

the United States Pharmacopeia
The law elevated the public health role of the United States Pharmacopeia because it defined a drug as “all medicines and preparations recognized in the United States Pharmacopeia (USP) or National Formulary (NF),” and defined adulterated drugs as those referenced in the USP and NF but differing from “the standard of …

What does USP mean on pills?

What is the generic name for valsartan?

Frequently asked questions about Diovan (valsartan) Diovan is the brand name and valsartan is the generic name for the same medication.

Does valsartan lower cholesterol?

Valsartan therapy was safe and well tolerated in our patient population. In conclusion, in addition to the marked decrease in blood pressure, valsartan significantly reduces total and LDL cholesterol levels and is neutral on glucose metabolism.

What percentage of valsartan is in hydrochlorothiazide?

» Valsartan and Hydrochlorothiazide Tablets contain not less than 90.0 percent and not more than 110.0 percent of the labeled amounts of valsartan (C 24 H 29 N 53 O 3) and hydrochlorothiazide (C 7 H 8 ClNO 4 S 2 ). Packaging and storage— Preserve in tight containers, and store at 25; excursions are permitted between 15 and 30.

How much valsartan is in a dilute solution?

Dilute an accurately measured volume of Solution 1 with Diluent to obtain a solution containing about 0.2 mg of valsartan per mL. Chromatographic system (see Chromatography 621)— The liquid chromatograph is equipped with a 265-nm detector and a 3.0-mm × 12.5-cm column that contains 5-µm packing L1.

How long does it take for valsartan to leave your system?

Valsartan peak plasma concentration is reached 2 to 4 hours after dosing. Valsartan shows bi-exponential decay kinetics following intravenous administration, with an average elimination half-life of about 6 hours. Absolute bioavailability for the capsule formulation is about 25% (range 10%-35%).