What is Hurst disease?

What is Hurst disease?

Acute haemorrhagic leucoencephalitis (AHLE), Weston-Hurst syndrome, or Hurst disease, is a rare fulminant and fatal demyelinating disease of the central nervous system. It is considered to be a rapidly progressive form of either acute disseminated encephalomyelitis (ADEM) or a variant of tumefactive multiple sclerosis.

What causes hemorrhagic encephalitis?

It occurs sporadically and may be considered as the most severe form of acute disseminated encephalomyelitis (ADEM) and is characterized by an acute rapidly progressive fulminant inflammation of the white matter. The cause is unclear but may be post-infectious (either viral or bacterial).

What is hemorrhagic Leukoencephalitis?

Acute hemorrhagic leukoencephalitis (AHLE) is a rare form of acute disseminated encephalomyelitis that is characterized by a brief yet intense inflammation in the brain and spinal cord. This attack critically damages the myelin, a protective covering of the nerve fibers.

Does ADEM cause brain damage?

ADEM typically damages white matter (brain tissue that takes its name from the white color of myelin), leading to neurological symptoms such as visual loss (due to inflammation of the optic nerve) in one or both eyes, weakness even to the point of paralysis, and difficulty coordinating voluntary muscle movements (such …

Is there a cure for ADEM?

ADEM is a rare disease and no medications have been specifically approved by the US Food and Drug Administration (FDA) to treat it, however, treatment for ADEM could include the following: High dose intravenous (IV) corticosteroids (typically methylprednisolone) are the front-line treatment for ADEM.

What is acute hemorrhagic edema of infancy?

Acute hemorrhagic edema of infancy (AHEI) is a benign type of leukocytoclastic vasculitis. It is a benign phenomenon although it manifests with fever, large palpable purpuric skin lesions, and edema. The presentation of AHEI can often resemble that of Henoch-Schönlein purpura.

What is myelitis?

Overview. Transverse myelitis is an inflammation of both sides of one section of the spinal cord. This neurological disorder often damages the insulating material covering nerve cell fibers (myelin). Transverse myelitis interrupts the messages that the spinal cord nerves send throughout the body.

What is acute hemorrhagic pancreatitis?

Acute hemorrhagic pancreatitis is an inflammation of the pancreas. It often occurs suddenly and quickly, and in some cases, could be fatal. So, what is it exactly? Acute pancreatitis occurs when the pancreas unexpectedly becomes swollen.