What is dynastat injection?

Dynastat is a painkilling medicine for use in adults for the short-term relief of pain after an operation. It contains the active substance parecoxib. How is Dynastat used? Dynastat is available as an injection and it can only be obtained with a prescription. Dynastat can be given into a vein or a muscle.

How do you administer dynastat?

The recommended dose is 40 mg administered intravenously (IV) or intramuscularly (IM), followed every 6 to 12 hours by 20 mg or 40 mg as required, not to exceed 80 mg/day.

How do you give an IV dynastat?

The IV bolus injection may be given directly into a vein or into an existing IV line. The IM injection should be given slowly and deeply into the muscle. Concomitant Use with Opioid Analgesics: Opioid analgesics can be used concurrently with parecoxib, dosing as described previously.

Is dynastat safe for pregnancy?

Dynastat is contraindicated in the third trimester of pregnancy (see section 4.3). There are no adequate data from the use of parecoxib in pregnant women or during labour. However, inhibition of prostaglandin synthesis might adversely affect pregnancy.

How do you dilute a dynastat?

DYNASTAT Injection is a white to off-white, preservative-free, lyophilised powder in a single-use vial. For intravenous (IV) or intramuscular (IM) administration, DYNASTAT Injection should be reconstituted with 2 mL sodium chloride solution (0.9% w/v), or a suitable alternative (see section 4.2).

Is Dynastat safe for pregnancy?

What is Dynastat 40 mg?

What Dynastat is for. This medicine is used for the prevention and treatment of pain. It can be used to relieve pain and reduce inflammation (swelling and soreness) which may occur after surgery. Although Dynastat can relieve the symptoms of pain and inflammation, it will not cure your condition.

How do you dilute a Dynastat?

How do you mix dynastat?

What is dynastat used for?

What Dynastat is used for. What Dynastat is for. This medicine is used for the prevention and treatment of pain. It can be used to relieve pain and reduce inflammation (swelling and soreness) which may occur after surgery.

Can dynastat be taken during pregnancy?

In animals, administration of prostaglandin synthesis inhibitors, including parecoxib, has been shown to result in increased pre- and post-implantation loss and embryo-foetal lethality (see sections 5.1 and 5.3). During the first and second trimester of pregnancy, Dynastat should not be given unless clearly necessary.

How long does it take for dynastat to work?

After a single dose, the duration of analgesia was dose and clinical pain model dependent and ranged from 6 to greater than 24 hours. The active ingredient in Dynastat is parecoxib (as parecoxib sodium). Dynastat contains 40 mg parecoxib per vial. Dynastat also contains dibasic sodium phosphate, phosphoric acid and sodium hydroxide.

Is Dynastat an effective injection for abdominal hysterectomy pain?

Dynastat injection was evaluated in single and multiple dose regimens in women with moderate to severe pain following abdominal hysterectomy. Single doses of Dynastat injection 20 and 40 mg IV were compared to placebo, morphine 4 mg IV and ketorolac 30 mg IV.