What are the doses for rivastigmine?
Adults—At first, 1.5 milligrams (mg) two times a day. Your doctor may gradually increase your dose as needed and tolerated. However, the dose is usually not more than 6 mg two times a day. Children—Use and dose must be determined by your doctor.
What strengths does rivastigmine come in?
Dosage Forms & Strengths
Can you overdose on rivastigmine patch?
Taking an overdose of rivastigmine may lead to convulsions (seizures) or shock. Some signs of shock are large pupils, irregular breathing, and fast weak pulse. Other signs of an overdose are severe nausea and vomiting, increasing muscle weakness, greatly increased sweating, and greatly increased watering of the mouth.
How do you give rivastigmine patches?
Apply the patch right away after removing it from the protective pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and hairless skin area on your upper or lower back, upper arm, or chest. Do not put the patch over rashes, cuts, or irritated skin.
What is rivastigmine 4.5 mg used for?
Rivastigmine is used to treat confusion (dementia) related to Alzheimer’s disease and to Parkinson’s disease. Rivastigmine does not cure either of these diseases, but it may improve memory, awareness, and the ability to perform daily functions.
How long is rivastigmine effective?
Conclusions: The rivastigmine transdermal patch is effective in maintaining cognitive function over 18 months of treatment in patients with mild-to-moderate AD.
Where should rivastigmine patches be placed?
Apply the patch to a clean, dry, and hairless skin area on your upper or lower back, upper arm, or chest. Do not put the patch over rashes, cuts, or irritated skin. Avoid putting the patch on areas where it could be rubbed off by tight clothing.
How often do you change rivastigmine patch?
Change your EXELON PATCH every 24 hours at the same time of day. You may write the date and time you put on the EXELON PATCH with a ballpoint pen before applying the patch to help you remember when to remove it. Change your application site every day to avoid skin irritation.
How long does a rivastigmine patch last?
Do not put a new patch in the same place for at least 14 days. Do not leave the patch on for more than 24 hours. It will not work as well after that time and it may irritate your skin. After removing a used patch, fold the patch in half with the sticky sides together.
What is the best medicine for dementia?
The cholinesterase inhibitors most commonly prescribed are: Donepezil (Aricept®): approved to treat all stages of Alzheimer’s disease. Rivastigmine (Exelon®): approved for mild-to-moderate Alzheimer’s as well as mild-to-moderate dementia associated with Parkinson’s disease.
How many times a day should I apply the rivastigmine patch?
For patients receiving less than 6 mg/day of oral rivastigmine and switching to the rivastigmine patch, apply one 4.6 mg/24 hours patch transdermally once daily. For patients receiving 6—12 mg/day of oral rivastigmine and switching to the rivastigmine patch, apply one 9.5 mg/24 hours patch transdermally once daily.
What is the dosage of rivastigmine transdermal system for Alzheimer’s disease?
The effective dosage of Rivastigmine Transdermal System in patients with severe Alzheimer’s disease is 13.3 mg/24 hours administered once per day; replace with a new patch every 24 hours. If dosing is interrupted for 3 days or fewer, restart treatment with the same or lower strength Rivastigmine Transdermal System.
How safe is rivastigmine patch for Alzheimer’s disease?
Alzheimer’s Association International Congress; Boston: Infrequent skin reactions at the application site of rivastigmine patch (4.6, 9.5 or 13.3 mg/24 h): analysis of 2 clinical studies reveals most are tolerable and manageable across all doses. July 13–18, 2013. [Google Scholar]
When to switch to rivastigmine transdermal system?
A patient who is on a total daily dose of less than 6 mg of oral rivastigmine can be switched to the 4.6 mg/24 hours rivastigmine transdermal system. A patient who is on a total daily dose of 6 mg to 12 mg of oral rivastigmine can be switched to the 9.5 mg/24 hours rivastigmine transdermal system.