Is nrx-101 a 5-HT2A antagonist?

Is nrx-101 a 5-HT2A antagonist?

The 5-HT2a receptor is a G protein-coupled receptor and a member of the serotonin family. It is known for its role in mediating certain antipsychotic effects. Lurasidone, the other active ingredient in NRX-101, is a 5-HT2a antagonist that is currently approved as an antipsychotic, and indicated for bipolar depression.

How long should nrx-101 be taken?

NRX-101’s proprietary combination of D-cycloserine and Lurasidone is designed to be taken orally, each day for approximately six weeks following an initial, single infusion of NRX-100 (ketamine).

What kind of drug is NRX 101?

NRX-101 is a patented, oral fixed-dose combination of two FDA-approved drugs: D-cycloserine, an NMDA receptor modulator; and Lurasidone, a 5-HT2a receptor antagonist that has been awarded Breakthrough Therapy Designation and a Special Protocol Agreement by the FDA. NRX-101.