Is caspofungin the same as micafungin?
In vitro, micafungin is considered more effective against C. glabrata because its minimum inhibitory concentration against C. glabrata is lower than that of caspofungin. However, in vivo, there is no significantly different effect between the two drugs.
Is mycamine the same as micafungin?
Micafungin, sold under the brand name Mycamine, is a echinochandin antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis.
Is Mycamine generic?
Micafungin for Injection is available in 50mg and 100mg strengths in 10mL single-dose vials. Fresenius Kabi announced the launch of Micafungin for Injection, a generic version of Mycamine (micafungin for injection; Astellas Pharma).
Who makes Mycamine?
Injection site reactions, including phlebitis and thrombophlebitis have been reported, at Mycamine doses of 50-150 mg/day. About Fujisawa Healthcare, Inc. Fujisawa Healthcare, Inc., headquartered in Deerfield, Ill., develops, manufactures, and markets proprietary pharmaceutical products in the United States and abroad.
Is mycamine generic?
What is Mycamine for?
This medication is used to treat a variety of fungal infections. It is also used to prevent fungal infections in patients who are having a stem cell transplant. Micafungin belongs to a class of drugs known as echinocandins.
What is caspofungin given for?
Caspofungin injection is used in adults and children 3 months of age and older to treat yeast infections in the blood, stomach, lungs, and esophagus (tube that connects the throat to the stomach.) and certain fungal infections that could not be treated successfully with other medications.
What do Echinocandins do?
Echinocandins are a class of antifungal drugs that inhibit the synthesis of β-glucan in the fungal cell wall via noncompetitive inhibition of the enzyme 1,3-β glucan synthase.
Which is better micafungin or caspofungin?
Micafungin 100 mg was slightly more effective (treatment difference, 4.1%; 95% CI, -4.4% to 12.3%) and micafungin 150 mg slightly less effective (treatment difference, -1.0%; 95% CI, -9.3% to 7.8%) than caspofungin, demonstrating that both micafungin regimens were noninferior to the caspofungin regimen ( table 4 ).
What is Mycamine (micafungin sodium)?
Mycamine (micafungin sodium) is an antifungal medication used to treat infections caused by the Candida fungus, and is also used to prevent Candida fungal infections in stem cell transplant patients.
Is micafungin protein-bound?
Similar to anidulafungin and caspofungin, micafungin is extensively protein-bound in the plasma (>99.5%) (Mycamine 2008). The effects of protein binding on the activity of echinocandins are not fully understood as studies on the effects of protein binding on echinocandin activity have reported conflicting results.
Does micafungin cause treatment failure?
Persistently positive culture results as a cause of treatment failure were seen more frequently in micafungin 150 mg group (23 patients) and the caspofungin group (18), compared with the micafungin 100 mg group (11) (table 6).